My diet:

E951 Aspartame

E951SweetenersOrigin: Lab-made
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Every diet

VeganYes

Amino acids made by fermentation.

Gluten-freeYes
HalalYes
KosherYes
KetoYes
Low-FODMAPYes
The short answer
Aspartame (E951) is a zero-calorie sweetener in diet soda. It's approved, but WHO's cancer agency called it "possibly carcinogenic" in 2023, and people with PKU must avoid it.
Use in moderation

Safe in small amounts; may bother some people or raise blood sugar.

E-numberE951
Comes fromLab-made
What it doesSweeteners
Glycemic index0
Daily limit40 mg/kg
Also calledAspartame, NutraSweet

Rules by country

🇺🇸 US FDAApproved with limits
🇪🇺 European UnionWarning label required
🇨🇦 Health CanadaApproved with limits
CaliforniaNo extra rules

Approved everywhere. Labels must warn people with phenylketonuria (PKU) because it contains phenylalanine. In 2023 the WHO's cancer agency classed it as "possibly carcinogenic" (2B) while JECFA kept its 40 mg/kg limit.

How much is too much? (Acceptable Daily Intake)

2.8 gper day is the safe upper limit

Based on 40 mg per kg of body weight (EFSA / JECFA). A 20 kg (44 lb) child: 800 mg a day.

What is it?

Aspartame is about 200 times sweeter than sugar. It breaks down in heat, so it's used in drinks, not baking.

Where it comes from: Made by joining two amino acids, aspartic acid and phenylalanine, usually produced by fermentation.

Why it’s in food

  • Sweetens diet sodas and gum
  • Replaces sugar in yogurt and desserts

Often found in

Diet sodaSugar-free gumLight yogurtTabletop sweeteners

Also listed as: Aspartame, NutraSweet, Equal, APM

Health & gut impact

Cancer classificationUnder study

IARC classified it as possibly carcinogenic (2B), based on limited evidence.

IARC Monographs Vol. 134 (2023)

PKUUnder study

Dangerous for people with phenylketonuria.

FDA 21 CFR 172.804

Daily limitConcern

A 70 kg adult would need over 9 cans of diet soda daily to reach the limit.

JECFA (2023)

What can I use instead?

Stevia

Ratio: Follow package

Best for: Drinks

Related

More sweeteners:

Common questions

Is Aspartame safe?

Use in moderation (55/100). Approved everywhere. Labels must warn people with phenylketonuria (PKU) because it contains phenylalanine. In 2023 the WHO's cancer agency classed it as "possibly carcinogenic" (2B) while JECFA kept its 40 mg/kg limit.

Is Aspartame vegan?

Yes. Amino acids made by fermentation.

Is Aspartame gluten-free?

Yes.

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Scientific sources & regulatory citations
  • 21 CFR 172.804 (US FDA)
  • EFSA OpenFoodTox: E951
  • IARC Monographs Vol. 134 (2023)
  • FDA 21 CFR 172.804
  • JECFA (2023)

Last checked against FDA, EFSA and Health Canada records: October 31, 2026 · INS 951 · CAS 22839-47-0